MagnaLink® Streptavidin Magnetic Beads 2.8 µm

M-1003
SKU Unit Size Price Qty
M-1003-010 1 mL
$306.00
M-1003-100 10 mL
$1,673.00
M-1003-050 5 mL
$1,026.00

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Specifications

More Information
Bead Size 2.8 µm
Loading Capacity ≥ 10 nmol/mg
Reactivity Biotin
Applications Antibody Labeling, Aptamers, In vitro Diagnostic (IVD), Laboratory Developed Tests (LDT), Analyte Specific Reagents (ASR), Next-Generation Sequencing (NGS), Photocrosslinking Studies
Recommended Storage 4°C

Documents

Technical Information

Product Description

MagnaLINK Streptavidin Magnetic beads are highly uniform, 2.8 micron-sized polymer-encapsulated (no exposed iron), super-paramagnetic beads containing covalently cross-linked streptavidin (Figure 1). MagnaLINK streptavidin magnetic beads are made by covalently cross-linking streptavidin to a hydrophilic surface using SoluLINK’s proprietary HydraLINK conjugation chemistry. The high surface area of these paramagnetic beads when combined with SoluLINK’s efficient linking chemistry produces the most consistent and highest biotin binding capacity (≥10 nmol/mg) of any uniform streptavidin magnetic bead on the market. Beads are supplied at 1% solids (10 mg/mL) in nuclease-free water with 0.05% sodium azide.

Figure 1. Scanning electron microscope image of MagnaLINK Streptavidin Magnetic beads.
A cross-sectional diagram of MagnaLINK Streptavidin Magnetic beads is illustrated below.
 

Features of our MagnaLINK beads

  • Highest free biotin binding capacity of any uniform bead (≥ 10 nmol/mg)
  • Binds 0.8 nmol/mg biotinylated oligonucleotide
  • Binds 0.75 nmol/mg biotinylated-IgG @ 4 biotins/IgG
  • Beads are encapsulated (no exposed iron)
  • Paramagnetic beads are highly uniform in size (2.8 + 0.2 microns)
  • Fast magnetic response time (60% w/w magnetite)
 

Binding Capacity Comparison: MagnaLINK Streptavidin Magnetic Bead Vs. Competitor's Bead of Similar Size

Ligand MagnaLINK 2.8 µm Binding Capacity Competitor's 2.8 µm Bead Binding Capacity
Free biotin ≥ 10 nmol/mg 0.65 - 0.90 nmol/mg
Biotinylated oligo (23-mer) ≥ 0.8 nmol/mg N/A
Biotinylated IgG (4 biotins per IgG) ≥ 0.75 nmol/mg (112 µg/mg) 0.65 - 0.90 nmol/mg (5 - 10 µg/mg)

MagnaLINK References:

  1. Moore R, Worrallo M, Mitchell P, Harriman J, Glen K, Thomas R. Immobilisation of Delta-like 1 ligand for the scalable and controlled manufacture of hematopoietic progenitor cells in a stirred bioreactor. BMC Biotechnology volume 17, Article number: 65 (2017).
  2. McCutcheon, K. Bandara, A.B. Zuo, Z. Heflin, J.R., Inzana, T.J. The Application of a Nanomaterial Optical Fiber Biosensor Assay for Identification of Brucella Nomenspecies. Biosensors 2019, 9, 64.
  3. Chatterjee G, Jimenez-Sainz J, Presti T, Nguyen T, Jensen R. Distinct binding of BRCA2 BRC repeats to RAD51 generates differential DNA damage sensitivity. Nucleic Acids Research, Volume 44, Issue 11, 20 June 2016, Pages 5256–5270.

 

 

NanoLINK References:

  1. Viktorovskaya O, Greco T, Cristea I, and S. Thompson. Identification of RNA Binding Proteins Associated with Dengue Virus RNA in Infected Cells Reveals Temporally Distinct Host Factor Requirements. PLoS Neglected Tropical Diseases 2016 Aug; 10(8): e0004921.
  2. Beaumont M, Tomazela D, and E. Escandón. Antibody-drug conjugates: integrated bioanalytical and biodisposition assessments in lead optimization and selection. AAPS Open volume 4, Article number: 6 (2018).
  3. Qian Q, Zhang Z, Orwig A, Chen S, Ding W, Xu Y, Kunz R, Lind N, Stamler J, and L. Yang. S-Nitrosoglutathione Reductase Dysfunction Contributes to Obesity-Associated Hepatic Insulin Resistance via Regulating Autophagy. Diabetes Volume 67, February 2018.
  4. Zhao Y, Valbuena G, Walker D, Gazi M, Hidalgo M, DeSousa R, Antonio J, Oteo Y.G., and A.R. Brasier. Endothelial Cell Proteomic Response to Rickettsia conorii Infection Reveals Activation of the Janus Kinase (JAK)-Signal Transducer and Activator of Transcription (STAT)-Inferferon Stimulated Gene (ISG)15 Pathway and Reprogramming Plasma Membrane Integrin/Cadherin Signaling. Molecular & Cellular Proteomics. 15 (1) 289-304, 2016.

Intellectual Property

SoluLink® Bioconjugation For Research Use Only. Not for use in diagnostic procedures. For additional licensing restrictions, please see the license agreement at vectorlabs.com/solulink-research-license.

Products are for research use only, not for use in diagnostic or therapeutic procedures or for use in humans. Products are not for resale without express written permission of Seller. No license under any patent or other intellectual property right of Seller or its licensors is granted or implied by the purchase unless otherwise provided in writing.

TriLink does not warrant that the use or sale of the products delivered hereunder will not infringe the claims of any United States or other patents or patents pending covering the use of the product alone or in combination with other products or in the operation of any process. All and any use of TriLink product is the purchaser's sole responsibility.

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